In 1990, Frank Niedecker takes over the management and pushes the internationalization of the company. In 1972, the registered trade mark poly-clip was announced worldwide. For reasons of capacity, the production of clips was moved to Gedern in 1970. In 1962, the company participated for the first time in the industry's leading exhibition IFFA in Frankfurt. The parent company of today's Poly-clip System, Niedecker Verschlußtechnik GmbH (NVT), was then founded in 1959. The trademark poly-clip was registered in 1958. During an exhibition in 1957, the idea of closing sausages with metal clips was born. In 1952, Herbert Niedecker, the son of the founder, takes charge of the company and its 50 employees. From 1950, punched and formed parts, mainly parts for brakes for the automotive industry are produced. In 1948, after the death of her husband, Elisabeth Niedecker took over the management of the company. From 1932 onwards, Niedecker has been a successful lead seal manufacturer in Germany and has already gained experience with closure systems the basis of today's clip closure. The company initially manufactured tools for the processing and forming of sheet metal. More information is available at EMBO Travel Grants.The founding of the Oswald Niedecker Metallwarenfabrik oHG in Frankfurt/Main dates back to 1 March 1922. Selection of awardees is handled directly by the organizer who will notify all eligible participants. Applicants do not need to apply separately for travel grants for this event but should indicate on the registration form whether they wish to be considered for a travel grant. Travel GrantsĪ limited number of travel grants are available for participants. The maximum size should be 120 cm width/150 cm height. If you are interested in this option, please contact for more details. If positions remain open future rounds of selection will be performed, therefore you might be notified later.įor participants that already started with their own iCLIP experiments at home, it will be possible to bring their own samples under certain conditions. Selected participants will be contacted by e-mail by February 1st, 2017. Applications will be evaluated and selected by the organisers based on suitability for the course. Only complete applications will be considered. Abstract of your current research (max.explain why you would like to attend, including what you can contribute and how you think you will benefit from the practical course.include your relevant skills, experience and qualifications which show that you would be suitable for the practical course. We will prioritise applications from junior researchers at the PhD and early postdoc stage.Īpplicants are required to provide the following information:.iCLIP or related technologies (Hits-CLIP, PAR-CLIP, ribosome profiling) as part of their project in the near future. participants should be likely to use e.g. The course content should be relevant to their research, i.e.Participants should have experience in experimental RNA biology.The course is limited to 18 participants, which will be selected according to the following criteria: Payment details will be sent to successful applicants. full catering (breakfast, lunch, dinner, refreshments).Organisers are encouraged to implement measures to make the meeting environmentally more sustainable. The hands-on sessions in the laboratory will be complemented by presentations by established scientists that will share their experience on using iCLIP to answer different biological questions.ĮMBO Courses and Workshops are selected for their excellent scientific quality and timelines, provision of good networking activities for all participants and speaker gender diversity (at least 40% of speakers must be from the underrepresented gender). We will further discuss the bioinformatics strategies for analysis of iCLIP data. We will guide the participants through the complete protocol, placing special emphasis on critical optimisation steps and controls. The major objective of this EMBO Practical Course is to disseminate the knowledge and proficiency in this technically challenging ribonomics method. Individual-nucleotide resolution UV crosslinking and immunoprecipitation (iCLIP) has established itself as a leading method to map the RNA interaction sites of a single RBP-of-interest with high resolution and in a quantitative manner. Understanding these interactions in a genome-wide manner is crucial for gaining a complete picture of an RBP’s specificity and function. In turn, RBPs can interact with hundreds to thousands of cellular RNAs by recognizing certain sequence motifs or structural elements. Throughout its life cycle, each RNA will interact dynamically with numerous RNA-binding proteins (RBPs) that determine how the RNA is processed, where it is localized, whether it is translated and finally how it is degraded.
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